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Dr. Ehrlich's lab is studying the involvement of two
aspects of epigenetics,
namely, human DNA methylation and chromatin proteins, in carcinogenesis,
the
FSHD syndrome (facioscapulohumeral muscular dystrophy), and the ICF
syndrome
(immunodeficiency, centromeric region instability, and facial anomalies).
This
research focuses on how alterations in chromatin proteins and DNA
methylation
occur and affect chromosome stability, long-distance chromatin looping, and
gene expression.
Dr. Ehrlich is a graduate of
Columbia University and the State University of New York at Stony Brook and
did her postdoctoral research at the Albert Einstein School of Medicine.
She was Chairman of the 1998 Gordon Conference on "DNA Alterations in
Transformed Cells" and the 1997 FASEB Conference on "Biological
Methylation" and founder, former president, and current Vice-President
of the DNA Methylation Society, an
international society with a lively e-mail network used to exchange
scientific information.
Dr. Ehrlich has
edited a book entitled "DNA Alterations in Cancer: Genetic and
Epigenetic Changes" (Eaton Publishers, 2000). To review its table of
contents, click on the book image below:
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