Case presentation:

A 9-year-old girl presents with proteinuria. One year previously she had been treated for streptococcal pharyngitis with a normal follow-up urinalysis. Four months previously she had an episode of fever followed by proteinuria and hematuria. At that time, her workup included the following:
Urinalysis with
25 red cells per high-powered field
3+ proteinuria (2.8 grams/24 hr)
Serum cholesterol of 378 mg/dl (normal <200 mg/dl)
Serum protein electrophoresis showed an increased alpha-2 band
BUN and creatinine were normal
BP 100/45
No edema
Negative anti-streptolysin-O titres and throat cultures

The current physical exam was unremarkable and the following labs were obtained:
Urine
Specific gravity 1.01, 1+ protein
BUN 15 mg/dl
Serum creatinine 0.4 mg/dl

Questions:

  1. Was the girl's presentation 4 month's previously related to her streptococcal pharyngitis 1 year previously?
  2. How would assess her presentation 4 month's previously?
  3. What to you think of her current presentation?