OLIGODENDROGLIOMA

A 38 year old female presents with a 4 year history of increasing headaches. In the last month she developed seizures but there is no response to anticonvulsivant therapy. MRI is done. It shows a well-defined area of abnormal T2 signal involving the left frontal and temporal lobe. There is mass effect, surrounding edema and irregular calcification.A biopsy is done.

1-The histologic section shows:

A-Macrophages and lymphocytes

B-Pleomorphic cells

C-The classical "fried-egg" appearance

D-Sclerosis

E-All of the above

Correct answer: C

2-The diagnosis in this case is:

A-Ammon’s horn sclerosis of epilepsy

B-Oligodendroglioma

C-Glioblastoma multiforme

D-Intracerebral abscess

E-None of the above

3-The prognosis of this entity is:

A-Good prognosis, 5 to 10 years survival

B-Bad prognosis, less than 2 years survival

C-Uncertain

D-Long survival, more than 15 years

E-None of the above

4-The recommended treatment of this disease is:

A-Only surgery

B-Only chemotherapy

C-Surgery plus chemotherapy

D-Only radiotherapy

E-Surgery plus radiotherapy

5-Radiographically this entity can show:

A-Cystic areas

B-Calcification

C-Surrounding edema

D-Solid areas

E-All of the above

6-The biological behavior of this disease is:

A-Never undergoes malignant transformation

B-It is a malignant tumor

C-It is an infectious process

D-Although relatively benign, it can undergo malignant transformation

E-Behaves as a chronic disease

Correct answer: D