PPT Slide
C. Cytokine therapy - The aim is to augment the antitumor response by increasing the levels of particular cytokines. Among those that have been tried are IL-2, IFN, GM-CSF, IL-7 and IL-12. Problems are the short half-life, toxicity, and non-specificity
D. Monoclonal antibodies - Have been used to deliver immunotoxins, radioisotopes, or chemotherapeutic drugs to tumor cells. New approaches utilize bivalent antibodies containing one arm that recognizes a T cell and another that recognizes a TAA as a mean