S6C25P19CPemphigoid


	S6C25P19-1: Chronic active, but atrophic, cicatricial pemphigoid. To the right, activity has again produced a sub-epidermal cleft; inflammation is prominent beneath the defect. To the left, the epidermis is attached and the disease is chronic, but inactive. The epidermis is atrophic; skin appendages are atrophic. A dilated sweat duct is represented in the reticular dermis near the left margin of the section.

Buttons below provide access to pictorials and to respective PARENT CHAPTERS.



S6C25P19-2: A zone of chronic active inflammation in this lesion of cicatricial pemphigoid (CP) is represented.

	S6C25P19-3: The exudate along the floor of the bulla contains neutrophils. Disintegrating neutrophils have impregnated the fibrin with basophilic nucleic acids. This alteration in tinctorial qualities is a marker for the release of digestive enzymes into either tissue, or fibrin; neighboring tissue will be partially digested by the activated enzymes. The dermis is fibrotic (a marker for chronicity). The infiltrates contain eosinophils (CP).

	S6C25P19-4: The fibrosing reaction also extends into the upper portion of the reticular dermis (CP).

S6C25P19-5: In this portion of the same lesion, the reaction is one of chronicity without an active component (CP).

S6C25P19-6: Lesions of cicatricial pemphigoid, in exposed sites, may be chronically eroded as in this example. The inflammatory infiltrates are dense. Granulation tissue along the surface is edematous.

S6C25P19-7 (cicatricial pemphigoid): Granulation tissue along the eroded surface is edematous. The inflammatory infiltrates contain plasma cells.

CLICK TO GO TO NEXT PAGE IN SEQUENCE

SELECTED READING

BACK (spatial sequence)

CLICK TO GO UP ONE PAGE (to return to parent textual page, if at LEVEL 3, or the return to HOME, if at LEVEL 2)

Green buttons provide access to two web sites, and mauve buttons to all of the SECTIONS of this SITE.

First two items to the right provide access to web sites