S5C12P6DLE


S5C12P6-1: The changes of LE are represented. The epidermis is atrophic. Green arrows identify migratory histiocytes at the dermal-epidermal interface. The thickened basement is convoluted and reduplicated.

S5C12P6-2: Mucinous changes are prominent in the reticular dermis of this lesion of LE. In the areas of prominent mucinosis, collagen bundles are reduced in size and widely spaced. Elastic fibers are more regular in distribution than collagen bundles in the zone of mucinosis (LE mucinosis ; alcian blue-PAS).

S5C12P6-3: LE mucinosis in different colors (colloidal iron)



S5C12P6-4: LE mucinosis with emphasis on the elastica and collagen. Elastica is black and collagen is red (Verhoeff-van Gieson). There is some degree of elastolysis in the zones of mucinosis.



	S5C12P6-5: In this lesion, the changes are compatible with senescent DLE. The interface is straight and the basement membrane is hyalinized.

S5C12P6-6: In this field, senescent changes are accompanied by fibrosis in the upper portion of the dermis. The patterns are sclerodermoid; they would be difficult to distinguish from those of superficial morphea.

S5C12P6-7: In this lesion of senescent DLE, the epidermis shows hyperkeratosis, hyperplasia of the superficial unit, an inconspicuous basal unit, and vacuolar changes at the dermal-epidermal interface. The dermis is relatively free of inflammatory cells. Focally, to the left, the basement membrane is coarsened and hyalinized.

Up a Page

last two (green) items along bottom row to right are web sites; all others in cluster provide access to SECTIONS of this SITE.