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S5C11P5-4: In lichenoid reactions, there is a potential for the epidermis to violate the boundary posed by the basement membrane. In such a circumstance, the epithelium invades connective tissue in patterns of
pseudoepitheliomatous hypreplasia. In evaluating dermal invasion by benign epithelium, a requisite finding is the extension of nests of bland, but hyperplastic, squamous cells into the reticular dermis in advance of
an induced stromal response. As a consequence, the infiltrating epithelium at the extremities tends to entrap connective tissue fibers of the preexisting reticular dermis (a variation of phenomena in the
‘perforating disorders”). The pattern in this field qualifies as pseudoepitheliomatous hyperplasia. The overall pattern identifies the lesion as hypertrophic LE (a variant of DLE).
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