S3C22P10-Lichen Planus-misc

S3C22P10-1: In this lesion of lichen planus, lytic defects in the epidermal domain are identified with blue arrows. The defect, near, but to the right of, the center of the field, shows a necrotic keratinocyte with lymphocytes and histiocytes in “satellite” cell patterns. Colloid bodies are present in the epidermal defects and in the dermal papillae. Infiltrates of lymphocytes and histiocytes are band-like; they hug the epidermis.

S3C22P10-2: At the dermal-epidermal interface in this lesion of lichen planus, there is active erosion of the basal unit of the epidermis. The epidermal defects are outlined superiorly by hypertrophied keratinocytes of the superficial unit-like type. The thin, acidophilic membranes outlined by blue arrows are reduplicated basement membranes. They provide a marker for sequential stages in the damage, and partial repair, of the basal unit of the epidermis.

S3c22P10-3: The incremental nature of the erosive process in lichen planus-like reactions is confirmed by observations of the complex nature of basement membranes (blue arrows) in sites of active disease.

S3C22P10-4: With this alcian blue-PAS stain, duplicated basement membranes, and the mucinous components of both the papillary dermis and the epidermis are demonstrated (lichen planus). In areas, the basement membrane is interrupted. In addition, the membrane varies in thickness and in the intensity of the stain.

 

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