S1C19P9-Cell Types, misc. Mast Cells

S1C19P9-1: Mast cells are natives of the dermis, but are more easily appreciated in disorders showing hyperplasia of mast cells, or mastocytomas. Mast cells may be ovoid in outline with no cell processes, or they may be stellate in outline, as in this field. The dendritic cells at the extremities of green arrows are fibrocytes of the papillary dermis. The dendritic cell at the extremity of the red arrow is a mast cell. Its dendrite is closely associated with the pigmented dendrite of a dermal melanophage (giemsa stain). The dendrites and cytoplasm of the mast cell are lavender. Dendritic mast cells might be characterized as “fixed.”

S1C19P9-2: Dendritic mast cells are present in the adventitia of this vessel of the reticular dermis.

S1C19P9-3: There is a mild hyperplasia of dendritic mast cells in the adventitia of this follicle.

S1C19P9-4: This perivascular space shows a hyperplasia of dendritic mast cells.

S1C19P9-5: Mast cells are rounded and polygonal in outline in this example of mastocytoma. Focally, the mast cells are clustered. The cells have oval nuclei with characteristic chromatin patterns, inconspicuous nucleoli, and lavender, granular cytoplasm. Mast cells are reactive for CD-117 (c-kit).

 

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