S15aC3aP1 Targetoid Hemangioma

S15aC3aP1-1: The epidermis is hyperplastic with irregular elongation of rete ridges. The papillary dermis is slightly widened. Vessels are increased in number in the upper portion of the reticular dermis. Some of the vessels near the interface between the papillary dermis and the reticular dermis are dilated. There are spotty, minimal perivascular infiltrates of lymphoid cells. The elongated vessel, to the left of the center of the field and near the interface between the papillary dermis and the reticular dermis, shows a focal area in which the endothelial cells bulge into the lumen. The patterns are basically those of an angiectasia. There are pigment deposits in the dermis near the deep margin of the field.

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S15aC3aP1-2: At a higher magnification, the endothelial cells are most prominent to the extreme left along the dilated vessel. In this same area, there are mild papillary patterns.

S15aC3aP1-3: The delicate papillae are lined by a single layer of bulging endothelial cells; these cells have uniform, round or oval nuclei and scanty cytoplasm. In the areas of endothelial hyperplasia, there is increased prominence of basement membrane. In the papillae, the fibrous fronds appear to consist almost entirely of duplicated basement membrane.

S15aC3aP1-4: Delicate papillae and slightly atypical endothelial cells are characteristic features in this field.

S15aC3aP1-5: The endothelial changes and the papillae are prominent focally along the dilated lumen of the vessel.

S15aC3aP1-6: Focally, delicate papillae are a prominent feature.

S15aC3aP1-7: Hemosiderin deposits are a prominent feature in the deeper portion of the dermis (targetoid hemangioma).

 

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