S13C21P19-1:The epidermis shows hyperplasia of the basal unit and an even greater hyperplasia of the superficial unit. There is a zone of parakeratosis at the surface. Focally, keratinocytes of the superficial unit show perinuclear vacuolization. The affected cells also show enlargement of the nuclei and variations in nuclear size and outline ( koilocytosis). The patterns basically are those seen in lesions of condyloma acuminatum.

S13C21P19-2: At higher magnification, the atypia in the areas of koilocytosis is moderate. There are scattered, atypical, dyskeratotic cells and occasional mitotic figures. The lesion shows markers for a papilloma virus infection but, from another perspective, the changes qualify as a moderate keratinocytic dysplasia (atypical condyloma acuminatum). In this lesion, a transitional stage from infection to mild/moderate dysplasia is represented; the lesion is at the borderland between verruca and keratinocytic dysplasia of bowenoid type.

GREEN BARS provide access to WEB SITES

MAUVE BARS provide access to each of the SECTIONS on this SITE

BEIGE BARS provide access to CHAPTERS oF this SECTION as a continuation of the cluster of vertically oriented BROWN BARS above

next PAGE along same tier in spatial sequence

BACK TO PREVIOUS PAGE along tier in spatial sequence

UP ONE PAGE (to next tier); if at tier 3 up to respective parent PAGE; if at tier 2, then up to HOME