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S12C11P1-2: Aggregates of epithelioid histiocytes are loosely spaced in the dermis and are associated with infiltrates of lymphoid cells. The granulomas are associated with multinucleated giant cells (
lupus vulgaris). Initially, this patient had been diagnosed as having sarcoidosis and was followed for several years. Following treatment with adrenocortical steroids, acid fast organisms were found in a
skin biopsy and the diagnosis was changed to lupus vulgaris. The patient had received x-irradiation and subsequently developed a squamous cell carcinoma in the site of the lupus vulgaris and irradiation.
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