S11C22aP17a-Invasive Fungal Infections

S11C22aP17a-1: Characteristic, broad, basophilic hyphae of mucormycosis are loosely spaced in necrotic tissue. The hyphae branch at wide angles and are non-septate.

S11C22aP17a-2: Characteristic organisms of mucormycosis infiltrate the wall of a dilated, muscular vessel (green arrows). Organisms are also in the lumen of the vessel. The organism of mucormycosis ignores tissue planes.

S11C22aP17a-3: Epidermis and the superficial portion of the dermis are necrotic. Septate hyphae, that are relatively uniform in diameter, infiltrate the necrotic tissue (fusarium).

S11C22aP17a-4: This organism in a burrow is tunga penetrans.

S11C22aP17a-5: Tunga penetrans.

S11C22aP17a-6: Tunga penetrans.

S11C22aP17a-7: The infiltrate of this lesion of leishmaniasis is composed of activated histiocytes and loosely spaced lymphocytes. Small, basophilic organisms are present in the cytoplasm of some of the histiocytes. With a PAS stain these organisms would not be positive. In this manner, the result would be different from the reaction in a lesion of generalized histoplasmosis.

S11C22aP17a-8: Leishmania organisms are represented in the cytoplasm of histiocytes.

 

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