Acute Myeloblastic Leukemia


Images:

Peripheral Blood

Bone Marrow

Bone Marrow, High Power

Acute myelogenous leukemia (AML) is characterized by the presence of immature hematopoietic cells in the bone marrow and blood. These malignant cells do not differentiate normally, and thus may block the differentiation of the remaining normal hematopoietic precursors. The diagnosis of AML is made when over 30% of the marrow cells are immature cells, called myeloblasts.

Clinical Manifestations: AML Presents clinically with features of bone marrow failure, including anemia, infections, bruising or bleeding. Leukemic infiltration of organs (e.g. central nervous system, lymph nodes, skin) may produce specific signs or symptoms. Without treatment AML is rapidly fatal.

 


Back to Leukemias ; Hematopathology ; Department of Pathology ; or Tulane University Medical Center .

 


 

Students wishing to review normal white cell development may click here. To review normal blood cells in general click here.


If you need more information, the best place on the internet to search is usually the National Library of Medicine.

Please send your comments ABOUT THE WEB PAGE to Robert McLay or John Krause .


by Robert McLay and John Krause . Copyright Tulane University