Inside the Tulane Cancer Center: Winter 1996/1997

Winder 1996/1997

Headlines in this Issue:
A Message from the Director
Tulane Programs Receive Accreditation
CAB Prepares for the New Year
It Couldn't Happen to Me
Mind, Body & Soul
Festival for Women: 1996 Revlon Run/Walk
The Breast Cancer Fund's Silver Tea
Peace of Mind: Breast Health Center

A CLOSER LOOK:
Designer Genes: A CLOSER LOOK
Oncology Update 1996
Frontiers in Oncology

AT A GLANCE:
Upcoming Events
Comings and Goings
Recent Honors and Awards
Acknowledgements, Contributions & Recognition

Index to all archived issues
Index to archived articles by topic
Editorial Staff & Contacts

A Message from the Director

Roy S. Weiner, M.D.
Director, Tulane Cancer Center

In our inaugural issue of Inside the Tulane Cancer Center, I discussed goals for 1997. One goal is to continue the development of our research base and to mold our research into clear-cut programs recognized as valuable to our scientific peer group and to those we serve. Another is to build, equip and use our new Comprehensive Cancer Center to provide our patients and our faculty a dynamic, friendly environment for excellent cancer care. A third is to develop a network of physicians and health care facilities and thereby extend the Tulane model of research-driven cancer care to as many patients as possible in this region.

In this and coming newsletters, I will provide readers with updates on our progress. Each issue of our newsletter will provide information about the exciting scientific activities at the TCC. This information will be provided in a our feature section called A Closer Look. In its first series, A Closer Look will highlight "disease management" - a term coined in response to today's health care trends.

In disease management, the characteristics of a population of individuals having a disease and the strategy for positioning or curing the disease is studied and analyzed. Following the analysis, programs and plans of care believed to be the "best practice" are developed. These best practice methods are then used to guide choices in the care of individual patients. The results, or "outcomes" of following best practices are monitored. The information gained in monitoring outcomes is then used to refine and improve a "best practice."

At the TCC, we are putting a new twist on disease management. We include not only clinicians, but basic, behavioral and other research scientists as members of our disease management teams. We draw upon current and emerging scientific knowledge in the design of our best practice models. At the Tulane Cancer Center our teams are Disease Oriented Task Forces.

The TCC currently has six functioning task forces: Lymphoid and Myeloid Malignancies, Breast Cancer, Prostate Cancer, Hepatocellular Carcinoma (Liver) and AIDS-related Cancers. In this issue we are featuring the work of the Lymphoid and Myeloid task force in an article entitled Designer Genes. In future issues, we will update you on the work of our other Disease Oriented Task Forces.

Tulane Programs Receive Accreditation

The Commission on Cancer of the American College of Surgeons or ACOS has granted four-year approval to the cancer program at the Tulane Cancer Center. Established in 1932, the ACOS Approvals Program designates that certain programmatic criteria thought important to cancer care have been met.

An integral part of a cancer program approved at the TCC is the tumor registry through which all patients diagnosed or treated for cancer are tracked. Information collected through the registry allows the TCC to participate in national studies that are designed to improve patient care. Only about twenty percent of the country's hospitals have ACOS approved cancer programs.

The Bone Marrow Transplant Laboratory at the Tulane University Hospital and Clinic has been awarded a two-year accreditation by the Commission on Laboratory Accreditation of the College of American Pathologists (CAP). The CAP is an international medical society composed exclusively of pathologists. It is widely considered the leader in laboratory quality assurance.

Dr. Alan Miller, Director of the Bone Marrow Transplant Program at the Tulane Cancer Center, was advised of this national recognition and is congratulated for what CAP deemed as the "excellence of the services being provided."

Tulane Cancer Center Community Advisory Board

Prepares for the New Year

At the December meeting, chairman Sam LeBlanc gave an an informative presentation to the Community Advisory Board concerning the uniqueness of the Tulane Cancer Center. While discussing the TCC's new tagline Your Partner for Life! LeBlanc commented, "It is important that we all remember that many people still associate cancer with certain death. We've got to let the community know that receivingcancer care at an academic cancer center is an opportunity for life!"

During the Director's Update, Dr. Weiner emphasized Mr. LeBlanc's theme by saying, "As the eyes, ears, and voices of the Tulane Cancer Center," the Advisory Board members play a critical role in promoting the TCC as the academic cancer care center for New Orleans, the state of Louisiana, and the greater gulf coast region.

Dr. Weiner's udate included a special gift presentation to founding chair Cathy Pierson. Thanking her for three years of hard work and dedication Dr. Weiner said, "All of us at the Cancer Center owe Cathy an enormous debt of gratitude. Her devotion and commitment to the Cancer Center continues to be extremely valuable."

Status reports were provided by each of the four committee chairs: Ethel C. Valz, Patient Support; Richard S. Friedman, Research Fellowship; Durinda Robinson, Fund-raising Event; and Gay LeBreton, Community Outreach.

Many thanks to Charlotte Zamjahn, Assistant Director of Development, for her help in organizing the Community Advisory Board. "The CAB is truly a prestigious group of individuals," said Mrs. Zamjahn, "who have pledged their commitment and support to the TCC. They are wonderful."

The mission of the Community Advisory Board is to evaluate and communicate community needs to help the TCC establish program priorities. It develops volunteer support services, provides matching funds to support the education of research fellows, and promotes the TCC as a community resource through several speakers bureaus, preventative screenings, and educational programs.

It Couldn't Happen to Me

Dr. Suzette Cullins live on WYLD-FM

Many women say "it couldn't happen to me," but this year alone 185,000 women will discover that they have breast cancer. In fact, every day in Louisiana, eight women are diagnosed with the disease and two women will die from it. Researchers tell us that, in general, African Americans have the highest mortality rate in the country for breast cancer. They attribute this disease to a number of factors, some of which are limited participation in cancer screening methods, poor access to health care, and socialization.

Councilwoman Ellen Hazeur-Distance

In at attempt to address these distressful facts, the Tulane Cancer Center, Tulane University Hospital and Clinic, Schwegmann's, and Clear Channel Broadcasting joined efforts to increase awareness of the general public during National Breast Cancer Awareness Month last October.

The It Couldn't Happen to Me Breast Cancer Awareness Rally took place on Saturday October, 26th. The rally was the brainchild of Dr. Suzette Cullins, and was held at the Schwegmann's Giant Supermarket located on Bullard Avenue in New Orleans East. The New Orleans East facility was chosen because of its high consumer traffic, customer base, and location. Dr. Cullins, along with others, answered questions, demonstrated self-breast examinations, using portable breast models, and recruited women to join the Friends for Life buddy-program.

Rep. Cynthia Willard-Lewis and Councilwoman Ellen Hazeur-Distance made special appearances in support of the event. In addition to the Tulane Cancer Center and the Tulane University Hospital and Clinic participating in the event, the Office of Public Health and Columbia-Lakeland were on hand to offer additional information and resources.

Mind, Body & Soul

In Louisiana, African-Americans have the highest mortality rate for breast, prostate, and lung cancer. In addition, they also lead the country in high mortality rates for diabetes, cardiovascular disease, and hypertension. Many of these diseases are not detected until excessive damage has been done, and in many cases, this damage is irreversable. In addition, a number of barriers exist which prevent early action such as: underserved communities, poor access to healthcare, and lack of knowledge.

In a collaborative effort, the Tulane Cancer Center and the Tulane University Hospital & Clinic developed a pilot program targeting the African American community. Mind, Body & Soul, is a community outreach and education program which offers valuable health information to minority consumers and is designed to heighten their awareness of important health issues.

"Increasing awareness of the need for prevention, early detection and treatment of all diseases is imperative." said Monique Ellis, Marketing Coordinator for the Tulane Cancer Center. "If we plan to decrease mortality rates, we must first, educate the community on the importance of changing behavior and lifestyles."

The campaign included a series of health related infomercials, which were broadwast on WYLD AM/FM during National Prostate Cancer and Breast Cancer awareness months (September and October). The radio spots featured the voices of Dr. Karen Friday, Ph.D. (Assistant Professor of Medicine, Endocrinology), Dr. Robert Metheney M.D. (Assistant Professor of Medicine, Cardiology), and Tulane Cancer Center members Rodney Davis, M.D. and Suzette Cullins, M.D.. The radio spots and the handbook were written and produced both Monique Ellis and Celeste Arnold, Public Relations Assistant for Tulane University Hosital & Clinics. This handy resource tool addresses early detection and prevention of various forms of cancer as well as information regarding to nutrition, diabetes, hypertension, and heart disease.

"Mind, Body and Soul is a health program that we are all very proud of." said Celeste Arnold. "It not only provides information on diseases that are more prevalent in the African-American community, but it introduces people to our Tulane physicians who specialize in those diseases. More importantly, this handbook focuses on prevention, which is the key to good health."

Festival for Women

1996 Revlon Run/Walk

The morning of Saturday, November 2nd, was cold and dreary. The overcast skies did not make much of a welcome to over 8,000 people who flocked into Tad Gormley Stadium at City Park in support of the 1996 Revlon Run/Walk for Women. But regardless of the weather, men, women and children braved the cold and put their best "feet" forward. Founded in 1994 by Lilly Tartikoff, the Revlon Run/Walk for Women in just two short years has become the largest 5K fund-raising event in California and the second largest 5K event in the country. Dedicated to the thousands of women who have and who will battle breast and ovarian cancer, this event celebrates the strength and courage of these women by bringing together people of all ages, races, and social status in a united effort to eradicate these diseases.

As the event's second host city and the first of it's kind in New Orleans, the 5K race and music festival raised $250,000 for breast and ovarian cancer research. One hundred percent (100%) of the event proceeds will benefit local programs dedicated to research, education, treatment, and enhancing the lives of New Orleans women. The Breast and Ovarian Cancer Support and Rehabilitation at the Tulane Cancer Center and the Newcomb College Center for Research on Women were just two of the many beneficiaries of this wonderful event.

The Breast Cancer Fund's

Silver Tea

It has been said that the friends you make and the conversation you have over tea are the most precious in life. The Breast Cancer Fund, with the help of the Tulane Cancer Center, held the first annual Silver Tea on Sunday, November 3, 1996. The event was held at the lovely Riverview Room in Jackson Brewery and was hosted by Lea Sinclair of the Windsor Court Hotel. The tea boasted the silver services from the finest homes and businesses in the city: Mrs. Margaret Kelly, Tulane University, Mrs. Peggy Wilson, Council-At-Large, Mrs. Anila Keswani, Taj Mahal Restaurant, Mrs. Myra Landry, The Black Butterfly, Mr. Keil Moss, Moss Antiques, and Mr. Charles Robinson, Robinson's Antiques all proudly displayed their services for everyone's view.

Andrea Martin, Executive Director and Founder of The Breast Cancer Fund was on hand to meet and greet guests and later challenged each and every women to become advocates for breast cancer. "Breast cancer must be eradicated in our daughters' lifetimes," said Andrea, " and until the means for cure and prevention are found, those at risk for surviving breast cancer - which is all women- must be educated and supported completely."

"Today's patron party begins our work for the Spring fund-raiser "Breast Cancer Survivors and Other Heroes," said Joann-Abbott Thaxton, marketing representative for The Breast Cancer Fund and owner of My Own Marketing, "we hope to continue to build strong partnerships within the Greater New Orleans and Tulane communities in support of our spring event."

In addition, the event promoted the Tulane Cancer Center's Friends for Life program. With the help of The Breast Cancer Fund, this program was established in April 1996, to educate women about their breast health. The free buddy-program is designed to motivate well women, heighten their awareness of breast health, and stimulate breast cancer survivors to become active in women's health issues. Over twenty women joined the program and participated in an "initiation" photography session. Over 300 women throughout the City have joined the "buddy-program." The program is featured at health fairs, screening programs, and cancer awareness events throughout the Greater New Orleans area.

For $50

You Can Get Peace of Mind

That's Worth a Million

Introducing the "One Stop"
Breast Health Center

Brest Self-Examination Instruction
Clinical Breast Examination and Total Care
Mammography and Heath Risk Reduction
Recieve your Mammography Results During your Visit!

If it is time for your annual mammogram, consider the advantages of "Breast Health" and call The Professionals at (504) 988-5800 to schedule your appointment.

Should any further follow-up be necessary, additional clinical services will be available to you at standard fees.

Designer Genes

A Closer Look
The Combined Task Force
on Lymphoid and Myeloid Malignancies
In more than 30 years of practice, Dr. German Beltran, a specialist in neoplasias and adult leukemias and lymphomas, has seen prospects for victims of this class of malignancies shift from almost certain death to increasing probability of cure, 30 percent or higher for non-Hodgkins lymphomas, for example. With some other types of cancers, results are even better; childhood leukemias, for example, are nearly all approaching cures. Progress may be even more rapid as a result of unique collaborations like the combined Lymphoid and Myeloid Task Forces of the Tulane Cancer Center.

"The task force brings together scientists doing basic research and clinicians who are able to help them point their research into a clinical context, to implement translational research and to prepare to move new knowledge into clinical application," said Dr. Beltran, Professor of Hematology/Oncology.

Beltran is among the most senior of the 30 members from a dozen departments that meet regularly to share information and to set priorities for research and clinical work. The task force, like others at the Cancer Center, is headed by a basic researcher, in this case Laura Levy, Professor of Microbiology and Immunology, and Barbara Beckman, Professor of Pharmacology.

One of the group's first tasks was to develop an algorithm for treatment of leukemias, lymphomas and other malignancies associated with blood and blood-making organs. The algorithm is an agreed-upon sequence of decision-making points that sets the patient's individual clinical and laboratory data in the context of the most effective and efficient therapies and the most recent research results. The result is a detailed treatment plan tailored to each patient's condition, stage of disease, history, general health, and other factors. The algorithm and resulting treatment plans also express an intersection between basic scientists and clinicians on the task force.

Dr. Beckman explained, "Tulane has always had the strength in basic research. What the task forces have done is to bring in the right clinicians, so that each enhances the other's perspective. The treatment team, in effect, is extended to include the researchers."

For example, the algorithm, along with the regular task force exchanges, keeps basic researchers up to date on what kinds of human cells may be available when they are ready to move their work a step nearer therapeutic application. Indeed, another goal of the combined lymphoid and myeloid task forces is to advise on the collection and storage of tissues that may be useful in research. Other task force priorities include updating the medical curriculum to keep abreast of the latest data and techniques and educating physicians and the public on both therapies and preventive measures.

For their part, clinicians learn of techniques and concepts developing in the laboratories and can advise on the results most likely to lead to better diagnostic tools or treatments. Biochemistry Professor Melanie Ehrlich, for example, refined a widely used test to make it so sensitive that a single cell with a particular chromosomal rearrangement associated with a specific cancer can be detected among millions of cells, even in the blood of healthy persons. In a different application, Dr. Alan Miller, Director of Bone Marrow Transplantation, is working with Dr. Ehrlich to use this technique to assess the effectiveness of leukemia treatments.

Such collaborations will eventually go even further as scientists learn to control genetic expression more precisely, and clinicians become ever more proficient at manipulating bone marrow cells and developing new techniques of delivering genetic information. In another example, Dr. Levy is working with Dr. Krishna Agrawal, Professor of Pharmacology, to alter the genetic composition of bone marrow cells in order to protect healthy cells from the effects of chemotherapy and radiation, which would improve the effectiveness of therapies already in use. Conversely, their work, and that of Drs. Beckman and Ehrlich, could lead to ways to alter tumor cells to make them more vulnerable to attack from the immune system. Among other projects are study of lymphomas that arise in HIV-infected patients and primate models to develop ways to deliver genetically altered cells to treat malignancies.

Dr. Beckman notes that effective gene therapy for leukemias and lymphomas awaits solutions to two problems: development of a reliable means to turn on and off selected gene expression, one of her areas of research; and a means to insure a sufficiently high level of the desired expression over a long period of time, an area of focus for Dr. Levy, as well as others on the task force. Clinicians could use bone marrow transplants, for example, to insert cells engineered to combine the resistance to chemicals and radiation with properties characteristic of healthy cells. Then the patient could be more safely treated to eliminate the malignant cells only.

This scenario may not be so far away. Currently, patients often receive "cocktails" of various compounds that attack malignant cells in a predetermined sequence of interactions. Similarly, Dr. Beckman and other members of the task force see the day when clinicians will be able to administer combinations of cells whose genetic expression is controlled and coordinated to result in cures.

Dr. Beckman noted that bone marrow transplant is now one of the most advanced approaches in terms of the interface of basic science and medicine, "but most centers do not have the scientific back up to ask more important questions that will lead to better therapies."

The collaborative relationships fostered by this and other Cancer Center task forces offer the key to successful translation of knowledge from the laboratory bench to the bedside. This partnership is unique to academic medical centers where basic science and clinical expertise offer natural synergies. As a direct result, Tulane patients receive rapid benefit from new research results and expert evaluation of their personal therapies. Patients everywhere will see earlier, more accurate diagnosis and treatment-even prevention-as clinical and basic science researchers accelerate the pace and productivity of their work.

Oncology Update '96

The third annual Oncology Update was held at the Tulane Cancer Center during October 5-6, 1996. The annual course addressed a wide range of topics in Lymphomas and Leukemia and explored new and evolving areas in clinical advances, basic science and supportive care.

"The response from attendees was very positive." said Dr. Alan Miller, Director, Bone Marrow Transplant Program and Chairman of 1996 Program Committee, "Presenters from Tulane and around the country did marvelous jobs of keeping us informed of breaking scientific developments in leukemia and lymphoma. New features of this year's program included a scientific poster session and tumor board style case reviews. From the response received, we will definitely keep these in future programs."

The featured lecture included the inaugural Jack Stuckey Lecture presented by Dr. Janet Rowly, the world's leading expert in the genetic abnormalities leading to leukemia. The program ended with a well attended lunch presentation at the Hyatt Regency by Jay Benear, M.D. of Cancer Care Associates in Tulsa, Oklahoma. Dr. Benear discussed the impact of managed care on oncology. "Valuable information like Dr. Benear's, " said Mr. Jim Yates, Executive Director,Tulane Cancer Center, "give Louisiana physicians an opportunity to learn from the experience of other markets where managed care is more prevalent." "The Program Committee and the Office of Continuing Medical Education did a fantastic job in producing a program the was attractive to and well received by the Medical Oncologists and Hematologists in our region." said Dr. Roy S. Weiner, Director of the Tulane Cancer Center and Program Director for 1996 Oncology Update, "All who worked had to make this program a success should be congratulated. We look forward to future "Updates" and other educational offerings of equal quality and value."

Frontiers in Oncology

The Tulane Cancer Center sponsored an extraodinary and unique symposium on Friday, December 13, 1996, entitled Frontiers in Oncology. Three outstanding leaders in oncology thrilled an audience of students, trainees, faculty, and community oncologists with state of the art information. Dr. Judah Folkman, of Harvard Medical School, discussed the control of tumor angiogenesis and it's potential for treatment of cancer. Dr. James Holland, of Mount Sinai School of Medicine, discussed viruses in the pathogenics of cancer. Together with the Departments of Surgery and Psychiatry, the Tulane Cancer Center planned and presented this educational program for the benefit of the community we serve.

Upcoming Events

	March 7, 1997 20th Annual Interdisciplinary Cancer Research Workshop Sponsored by the Cancer Association of Greater New Orleans. Presented by LSU's Stanley S. Scott Cancer Center in partnership with the Tulane Cancer Center. Contact: Brooke Thacker, Tulane Anatomy Dept., (504) 988-5258
	April 10, 1997 Friends for Life Anniversary Celebration Tulane Cancer Center Contact: Keadren Green, (504) 988-6060 kgreen2@tulane.edu
	April, 1997 3rd Annual Louisiana Breast Cancer Task Force 5K Fun Walk Contact: Janina Simmons, LBCTF, (504) 454-0066
	May 9, 1997 Spring Gala: Breast Cancer Survivors and Other Heroes Fund-raiser New Orleans Sheraton; Armstrong Room Contact: Joann Abbott-Thaxton, The Breast Cancer Fund, (504) 522-9369
	July, 1997 Grand Opening Celebration Tulane Cancer Center Comprehensive Clinic Contact: Dr. Roy S. Weiner, TCC, (504) 988-6060 rweiner@tulane.edu
	September, 1997 Sports For Life Tournament Teaming Up Against Prostate Cancer Contact: Keadren Green, TCC, (504) 988-6035 kgreen2@tulane.edu

Comings and Goings

Welcome....
We are pleased to announce the appointment of Dr. William McKinnon as Professor of Surgery and Chief of the Tulane Cancer Center's Program in Clinical Breast Diseases. Dr. McKinnon comes to us from the Ochsner Foundation and brings expertise and recognition as a national authority on the management of breast diseases. He will sead the Tulane Cancer Center's effort to develop this region's outstanding center for the prevention, diagnosis, and management of breast diseases. For further information about the Breast Health Program and Dr. McKinnon please call the Tulane Cancer Center.

Farewell to....
The Tulane Cancer Center would like to wish a fond farewell and best of luck to the following individuals:

	Linita McDonald Office of Clinical Research
	Susan Halabi, Ph.D. Assistant Director, Office of Clinical Research

Thanks for your dedication and hard work while here at the Cancer Center. We are confident that you will succeed in future endeavors.

Recent Honors and Awards

	Laura Levy, Ph.D., Associate Professor Microbiology, was selected as the co-chairperson for the Oncogenesis Session of the 8th Workshop on the Photogenesis of Animal Retroviruses held in Saint-Malo, France, 23-25 October, 1996.
	Griselda Gutnisky, M.D., Assistant Professor Psychiatry/Neurology, is the recipient of a $15,000 grant from The Breast Cancer Fund. The grant was awarded to Dr. Gutnisky for the continued development of a support program for psychosexual rehabilitation of breast cancer patients.
	Melvin C. Gitlin, M.D., FACPM, Director of the Pain Management Center, was recently appointed to the inaugural Advisory Council of the American Alliance of Cancer Pain Initiatives. The group has been mandated to provide national leadership and develop policy. Dr. Gitlin was also appointed to the American Board of Pain Medicine Examination Council.
	Andrew V. Schally, M.D., Ph.D., Professor of Experimental Medicine has received a one-year CapCURE research awared in the amount of $100,000 for his proposal "The Development of New Methods, Utilizing Peptide Analogs for the Treatment of Androgen-Independent Prostate Cancer."
	Krishna Agrawal, Ph.D., Professor of Pharmacology, was recently awarded two one-year grants from the National Institute of Health. The first, in the amount of $150,00), for his proposal "Novel Approaches to Antiviral Chemotherapy." and the second, in the amount of $140,000, for his proposal "Mechanisms of Hematological Toxicity of Anti-AIDS Drugs.
	Steven Arnold, Ph.D., Assistant Research Professor, was awarded $12,000 by the Cancer Association of Greater New Orleans (CAGNO) for his proposal "Organochlorine pesticides as estrogens in human breast cancer cells."
	William Toscano, Jr., Ph.D., Professor and Chairman of the Department of Environmental Health Sciences received a one-year Scholarship for Bioenvironmental Research from Texaco, Inc., in the amount of $50,000.

Acknowledgements

Contributions & Recognition

	Since its opening on June 1, 1996, the Breast Health Clinic has served over 400 women in the community. The manager of the clinic, Maureen Sintich, RNC, MSN, FNP-C, has done an excellent job promoting the facility to the community, provid-ing patient support and screening services.
	The Friends for Life program has recruited over 300 women to participate in its buddy-program since the launch of the program in April, 1996. Monique Ellis, TCC Marketing Coordinator, and Joann Abbott-Thaxton, Marketing Representative for The Breast Cancer Fund, have done an exemplary job targeting women in the community by developing and supporting special events to promote the program throughout the Greater New Orleans Area.
	Thanks to the support of many Tulane University Hospital & Clinic employees and our own Cancer Center members, we have participated in over 50 educational health fairs throughout the community. The fairs promote prevention, early detection and treatment of various types of cancer. In addition, they promote our psychosocial and clinical services, as well as, our Friends for Life buddy program.
	The Marketing and Public Relations Department of the Tulane University Hospital & Clinic provides financial support to the Tulane Cancer Center for a variety of projects. Beth Branley and her staff continue to support the Cancer Center in its efforts and depict an ideal model of teamwork and collaboration.

INSIDE THE TULANE CANCER CENTER
Your Parter for Life!

Editorial Staff & Contacts

EDITORIAL
Editor: DR. ROY S. WEINER
Managing Editor: JAMES R. YATES
News & Features Editor: MONIQUE ELLIS

PUBLISHING Publisher: BETH BRANLEY, TUHC
Art: STEVEN PIERRE, TUHC

Sponsored in part by:
TULANE CANCER CENTER
(504) 988-6060
Web site: http://www.som.tulane.edu/cancer

FRIEDLER CANCER COUNSELING CENTER
(504) 988-2120

THE PROFESSIONALS Tulane Referals Office
1-800-588-5300 (Physicians)
1-800-588-5800 (Patients)

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