Inside the Tulane Cancer Center June 2004 Newsletter Accolades: Faculty Honors and Awards

Recent Publications
Grants Awarded or Scored Favorably
Presentations
Others Faculty Honors and Awards
Research Day student winners and their faculty sponsors

Recent Publications

• Bazzano LA, He J, Muntner P, Vupputuri S, Whelton PK: Relationship between cigarette smoking and novel risk factors for cardiovascular disease in the US population. Annals of Internal Medicine, 138:891-897, 2003.
• Bennouna S, Bliss SK, Curiel TJ, Denkers EY: Cross-talk in the innate immune system: neutrophils instruct recruitment and activation of dendritic cells during microbial infection. J Immunol, 171:6052-8, 2003.
• Cox MB, Miller III CA: Pharmacological and genetic analysis of Hsp90 isoprotein-aryl hydrocarbon receptor complexes. Molecular Pharmacology, 64:1549-56, 2003.
• Erfurth F, Hemenway CS, deErkenez AC, Domer PH: MLL fusion partners AF4 and AF9 interact at subnuclear foci. Leukemia, 18: 92-102, 2004.
• Kawakami Y, Curiel TJ, Curiel DT: Cancer gene therapy and immunotherapy. In Cancer Chemotherapy & Biologic Response Modifiers - Annual 21, Elsevier Press, 2004.
• Krause JR, Shadhidi-Asl M: Molecular pathology in the diagnosis and treatment of non-Hodgkin's lymphomas. J Cellular and Molecular Medicine, 7:494-512, 2004.
• Landry SJ: Structure and energetics of an allele-specific genetic interaction between dnaJ and dnaK: correlation of nuclear magnetic resonance chemical-shift perturbations in the J-domain of Hsp40/DnaJ with binding affinity for the ATPase-domain of Hsp70/DnaK. Biochemistry, 42(17):4926-4936, 2003.
• Lasky JA, Ortiz LA, Brody AR: Chronic lung injury and fibrosis: potential roles for TNF-a, PDGF, CTGF, and TGF-b. In: Lung Injury: Mechanisms, Pathophysiology, and Therapy. RH Notter, BA Holm, JN Finkelstein, Eds. Marcel Dekker, New York, 2003.
• Sikka SC: Role of oxidative stress response elements and antioxidants in prostate cancer pathobiology and chemoprevention - a mechanistic approach. Current Medicinal Chemistry, 10: 2679-2692, 2003.
• Sikka SC, and other members of a Cleveland Clinic Foundation Study Group: Enhanced chemiluminescence assay versus colorimetric assay for measurement of the total antioxidant capacity of human seminal plasma. J Andrology, 5: 676-80, 2003.
• Wittung-Stafshede P, Horne BE, Guidry J, Landry SJ: The J-domain of Hsp40 couples ATP hydrolysis to substrate capture in Hsp70. Biochemistry, 42(17):4937-4944, 2003.
• Zhu Y, Jones FE: The ErbB signaling network is coordinately expressed and activated in the mouse prostate. Prostate, 60:68-75, 2004
• Zou W, Wei S, Curiel TJ: "Dendritic Cells." In Gene Therapy. D. Curiel and J. Douglas, Eds. Blackwell Publishing, 2004.

Grants Awarded or Scored Favorably

• Asim B. Abdel-Mageed, Ph.D.
  Functional Characterization of Two Novel Human Prostate Cancer Metastasis Related Genes, Idea Development Award, Department of Defense Prostate Cancer Research Program, $554,525.
• Arnold R. Brody, Ph.D.
  • Training in Lung Molecular and Cell Pathobiology, NIH/NHLBI, $902,968 total direct, 9/03 - 3/08.
  • Dr. Brody's renewal, TNF-a to TGF-b Signal Transduction, 2 R01 ES06766-11, received a favorable score - 9th percentile. The grant is for a period of five years, 7/04 - 6/09, $1,254,655 total direct.
• Tyler J. Curiel, M.D., M.P.H.
  • Novel Studies of Sinonasal Undifferentiated Carcinoma, CAGNO, $7,500, 3/04 - 3/05.
  • CXCD 4/SDF-1 Signals in Ovarian Cancer, NCI, $1,850,000 total direct requested (final award amount pending), 7/04 - 6/09.
• Prescott Deininger, Ph.D.
  • Dr. Deininger received a favorable score - 9th percentile - on his NCRR grant application entitled Mentoring a Program in Cancer Genetics. His application is for five years, $7,500,000 total direct.
  • Subcontractor on Louisiana's NSF EPSCOR grant, recently renewed for three years. This grant supports scientific infrastructure in the state and a large scientific project supporting a collaboration between LSU (Baton Rouge), LSU Health Sciences Center (New Orleans), Tulane and Xavier to develop new and better approaches to high throughput genomics.
• Frank Jones, Ph.D.
  A five-year renewal of his R01 grant entitled ErbB4 Signaling in the Normal and Neoplastic Breast was recently awarded, $1,204,045 total direct, 7/04 - 6/09.
• Samuel J. Landry, Ph.D.
  Substrate Capture in Hsp70 Catalyzed by the Hsp40 J-Domain, NSF (MCB-0349578), $505,050 total direct, 2/04-1/09.
• Arthur J. Lustig, Ph.D.
  Dr. Lustig received a favorable score - 5.7th percentile - on his NIH, R01 grant entitled Eukaryotic Telomere Dynamics. His application is for five years, $1,125,000 total direct.
• Suresh C. Sikka, Ph.D.
  Dr. Sikka received a training grant from Lilly-ICOS, LLC, to train and manage a quality control and quality assurance program for standardized semen analysis, $414,375, 10/03 - 2/05.
• Paul K. Whelton, M.D., M.Sc.
  Tulane University Regional Bio-Containment Laboratory (Program Director: Andrew Lackner, D.V.M., Ph.D.), NIH/NIAID, $13,656,935. This award is designed to support construction of an approximately $20 million biosafety laboratory at the Tulane University National Primate Research Center. It also reflects the initiation of a 20-year cooperative agreement to work with scientists at the NIAID on biosafety initiatives.

Presentations

• Barbara Beckman, Ph.D.
  Much Huffing About HIF: The Story of Hypoxia-Inducible Factor and its Biomedical Relevance. Ochsner Clinic Foundation, Division of Research, January 2004.
• Tyler J. Curiel, M.D., M.P.H.
  • Curiel TJ, Landry SJ, Morris CA, Brumlik M, Joshi V, Nelson A, Hawkins C, Alvarez X, Lackner A, Mohamadzadeh M: Peptides identified through phage display direct immunogenic antigen to dendritic cells. Keystone Symposia 2004.
  • Curiel TJ, Landry SJ, Morris CA Joshi V, Berggren R, Mohamadzadeh M
    Targeting HCV NS3-NS4A to Dendritic Cells (DC) via DC-Binding Peptides Induces Potent T Cell Immunity In Vivo. AASLD Meeting, Boston, October 2003.
  • Brumlik MJ, Wei S, Burow ME, Curiel TJ
    Identification of gene encoding a novel mitogen-activated protein kinase in Toxoplasma gondii. American Society for Microbiology Southern Meeting, New Orleans, October 2003.
  • Presented at the Annual Meeting South Central Branch, American Society for Microbiology, October 2003:
    • Curiel TJ, Landry SJ, Morris CA, Brumlik M, Joshi V, Nelson A, Hawkins C, Alvarez X, Lackner A, Mohamadzadeh M: Peptides identified through phage display direct immunogenic antigen to dendritic cells.
    • Curiel TJ, Olson S, Brumlik M, Finstad K, Hawkins C, Alvarez X, Klaenhammer T, Mohamadzadeh M: Lactobacilli activate dendritic cells that skew CD4+ and CD8+ T cells to Th1 polarization.
    • Wei S, Daniel B, Curiel TJ
      Pyridinylimidazole drugs designed to block p38 MAPK activation treat Toxoplasma gondii infection.
• Frank E. Jones, Ph.D.
  ErbB4: Guardian of the Breast, Department of Molecular and Cellular Oncology, M.D. Anderson Cancer Center, December 2003.
• John R. Krause, M.D.
  • Correlation of Peripheral Blood Smear and Bone Marrow Morphology, American Society of Clinical Pathology, New Orleans, December 2003.
  • Hematology: Review and Update of Selected Topics, American Society of Clinical Pathology, Las Vegas, March 2004.
  • Peripheral Blood Review and Interpretation, American Society of Clinical Pathology, Chicago, April 2004.
• Charles A. Miller III, Ph.D.
  Hsp90 Chaperone Complexes and Aryl Hydrocarbon Receptor Signaling, Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, KY, November 2003.

Other Honors and Awards

• Asim Abdel-Mageed, D.V.M., Ph.D.
  • Member, Tuskegee University/University of Alabama-Tuscaloosa External Program Advisory Committee for Project EXPORT, a $7.5 million project examining the health disparities experienced by African-Americans in Alabama's Black Belt
  • Named an American Cancer Society Research Scholar by the American Cancer Society
  • Asked to participate as a representative for Tulane on a Louisiana Cancer Research Consortium Task Force to propose a Cell Analysis Core to meet the needs of the Consortium scientists at Tulane and LSU
• Arnold R. Brody, Ph.D.
  Study Section participation:
  • NIH (NHLBI), National Heart, Lung, Blood Institute, Special Review Committee for Program Project Grant/PO1, Lung Fibrogenesis and the Biology of Fibroblast, Rockville, M.D., February 2004.
  • NIH (NHLBI), National Heart, Lung, Blood Institute, Special Review Committee for Program Project Grant/PO1, Regulation of Respiratory Epithelial Cell Homeostasis, Rockville, M.D., February 2004.
  • Chairman, NIH (NHLBI), National Heart, Lung, Blood Institute, Special Emphasis Panel Granulomatous Lung Inflammation in Sarcoidosis, Rockville, M.D.., March 2004.
  • University of California, Tobacco-Related Diseases Research Program - Pulmonary Disease Review Committee, San Francisco, April 2004.
• Tyler J. Curiel, M.D., M.P.H.
  • Bouquet Award for civic service from The Gambit
  • Featured in "Random Samples," Science, 303:37, 2004.
  • Featured in La Prensa, Louisiana's Spanish-language newspaper.
  • Invited speaker, Walker's Cay Colloquium on Immunology, March 2004.
  • Set world record for 24-hour basketball dribble, 108.41 miles, Bounce For Life event, December 15-16, 2003.
  • Featured along with Tulane medical student Andy Martin in a Wall Street Journal cover story, April 1, 2004.
  • Recently promoted to professor with tenure
• Laura S. Levy, Ph.D.
  Selected chairperson of the Virology Study Section, Center for Scientific Review, National Institutes of Health, through June 2005.
• Suresh C. Sikka, Ph.D.
  Received first-prize award of $1,000 on his presentation on intralesional interferon alpha 2B therapy in Peyronie's patients, Annual Meeting of Sexual Medicine Society of North America, Denver, 2003.
• Ralph L. Corsetti, M.D.
  2004 Leonard Tow Humanism in Medicine Award presented by The Arnold P. Gold Foundation in recognition of exemplary compassion, competence and respect in the delivery of care.
  This honor was bestowed upon Dr. Corsetti at the Tulane School of Medicine's Diploma Ceremony on May 22, 2004.

Return to the June 2004 "Inside the Tulane Cancer Center" newsletter.

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Tulane Cancer Center
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