Tulane Cancer Center Members: J
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Jayawickramarajah, Jeter, Johnson, Jones, Jovov

Janarthanan Jayawickramarajah, Ph.D.
Assistant Professor of Chemistry
TCC Contributing Member
jananj@tulane.edu
(504) 862-3580, (504) 865-5596 fax
2015 Percival Stern Hall, 6400 Freret St., New Orleans, LA 70118
Homepage:
http://chemistry.las.tulane.edu/JanansGroup.html

Biographical Narrative:
Janarthanan Jayawickramarajah received his B.S. degree (with honors) in chemistry and a minor in anthropology from the University of North Carolina at Chapel Hill in 2000. He obtained a Ph.D. in organic chemistry from the University of Texas at Austin in 2005. For his graduate work on molecular recognition and self-assembly of synthetic nucleic acid bases, he has received the Dorothy Banks Research Fellowship and The College of Natural Sciences Dean's Excellence Award. After completion of a postdoctoral stint at Yale University focusing on protein recognition and DNA self-assembly, he joined the faculty at Tulane (August 2007). Currently, his research focuses on the development of designer molecules that have the unique ability to undergo specific molecular recognition events in a stimulus responsive manner.

Selected Publications:

• Harris DC, Chu X, Jayawickramarajah J. DNA-small molecule chimera with responsive protein-binding ability. Journal of the American Chemical Society, 2008 Oct 15 (epub ahead of print).
• Pierce SE, Sherman CL, Jayawickramarajah J, Lawrence CM, Sessler JL, Brodbelt JS. ESI-MS characterization of a novel pyrrole-inosine nucleoside that interacts with guanine bases. Anal Chem Acta. 2008 Oct 3;627(1):129-35. Epub 2008 Apr 15.
• Jayawickramarajah J, Tagore DM, Tsou K, Hamilton AD. Allosteric control of self-assembly: modulating the formation of guanine quadruplexes through orthogonal aromatic interactions. Angew Chem Int Ed Engl. 2007;46(40):7583-6.
• Tagore DM, Sprinz KI, Fletcher S, Jayawickramarajah J, Hamilton AD. Protein recognition and denaturation by self-assembling fragments on a quadruplex scaffold. Angew Chem Int Ed Engl. 2007;46(1-2):223-5.
• Sessler JL, Lawrence C, Jayawickramarajah J. Molecular recognition via base-pairing. Chem Soc Rev, 36:314-325, 2007.

James R. Jeter, Jr., Ph.D.
Professor of Anatomy (Structural and Cellular Biology)
Co-Director of Graduate Program in Structural and Cellular Biology
TCC Contributing Member
jjeter@tulane.edu
(504) 988-2745, (504) 988-1687 fax
1430 Tulane Ave., Box SL-49, New Orleans, LA 70112-2699
Homepage on the Anatomy website:
http://www.som.tulane.edu/anatomy/faculty/jeter.html

Biographical Narrative:
Dr. Jeter received his B.S. in Zoology in 1965 from Texas Technological College. He received his Ph.D. in 1973 from The University of Texas Medical School at San Antonio. His doctoral studies were carried out under the direction of Dr. Ivan Cameron and focused on the changes in the non-histone proteins associated with the cell cycle. Dr. Jeter then carried out post-doctoral studies for 3 years with Dr. Harold Rusch at the McArdle Laboratories for Cancer Research at the University of Wisconsin, continuing his work on non-histone proteins and the cell cycle. Dr. Jeter joined the Tulane faculty in 1975 as a member of the Anatomy Department. Dr. Jeter has served on the editorial boards of Cell and Tissue Kinetics, Cell Proliferation and Cell Biology: A Series of Monographs and has served as a grant reviewer for NSF, the Louisiana State Board of Regents-Cancer Division. Dr Jeter's primary research interest deals with the relationship between cell proliferation and cell differentiation in normal and cancer cells. In particular, his lab has concentrated on the role of protein kinases and protein phosphorylation in the control of proliferation and differentiation.

Selected Publications:

• Patterson KK, Beckman BS, Klotz DM, Mallia CM, Jeter Jr JR Dexniguldipine hydrochloride, a PKC-specific inhibitor affects cell cycle, differentiation, P-glycoprotein levels and nuclear proteins in Friend erythroleukemia cells. J Cancer Res and Clin Onc 122: 465-475 (1996)
• D'Souza FM, Sparks RL, Chen K, Kadowitz PJ, Jeter Jr JR. (2001) Antiproliferative effect of eNOS gene on vascular smooth muscle cells: involvement of PKA in induction of p53 and p21. Am J Phys (in press).

Carolyn C. Johnson, Ph.D., N.C.C., L.P.C.
Associate Professor of Community Health Sciences
TCC Contributing Member
cjohnso5@tulane.edu
(504) 988-4068, (504) 988-3540 fax
1430 Tulane Ave., Box SL-29, New Orleans, LA 70112-2699
Homepage on the CHS website:
http://www.tulane.edu/~chs/faculty/johnsonc.html

Biographical Narrative:
After obtaining a business degree from Soulé College, New Orleans, and extensive experience in the business arena, Dr. Johnson received her undergraduate degree in Psychology from the University of New Orleans in 1982, a Master of Science in Clinical Psychology from San Diego State University in 1985, and a Ph.D. in Applied Biopsychology from the University of New Orleans in 1990. Dr. Johnson is a Clinical Associate Professor in the Department of Community Health Sciences, Tulane University School of Public Health & Tropical Medicine and has been associated with the Tulane Center for Cardiovascular Health since 1986. Dr. Johnson's primary area of research is behavioral medicine, specifically those lifestyle choices that can contribute to health or disease such as tobacco and alcohol use, diet, sedentary behavior, teen pregnancy and stress. Most of Dr. Johnson's research has been school-based in the elementary, middle and high school grades in a health education/health promotion capacity. Studies that she designed, implemented and evaluated in the Bogalusa Heart Study included assertive communication and learned helplessness, as well as Type A behavior, alcohol and tobacco use. Every year she is involved in and chairs grant review panels for the U. S. Army in their prostate and cancer programs. Regarding health promotion for the prevention of cancer, Dr Johnson has been involved in promoting the 5-a-day concept and smoking prevention among high school students. She has conducted a stress reduction program for New Orleans inner-city school teachers and developed, implemented and evaluated the Heart Smart Family Health Promotion Program for high risk children and their parents. The field of school-based health education and promotion is especially important because of the need for children and adolescents to learn healthy lifestyles at young ages in order to establish good habits over a lifetime.

Selected Publications:

• Beech BM, Rice R, Myers L, Johnson CC, Nicklas TA. Knowledge, attitudes and practices related to fruit and vegetable consumption of high school students. J Adol Health 24(4): 244-250 (1999)
• Nader PR, Stone EJ, Lytle LA, Perry CL, Osganian SK, Kelder S, Webber LS, Elder JP, Montgomery D, Feldman HA, Wu M, Johnson CC, Parcel GS, Luepker RV. Three-year maintenance of improved diet and physical activity. The CATCH Cohort. Arch Ped Adol Med 153: 695-704 (1999)
• Johnson CC, Shi R, Farris R, Webber LS, Nicklas TA. Social support and self-efficacy for the consumption of fruit and vegetables by adolescents: "Gimme 5" - A fresh nutrition concept for students. Ecol Food Nutr 39: 357-374 (2000)
• Johnson CC, Li D, Epping J, Lytle LA, Cribb PW, Williston BJ. A transactional model of social support, self-efficacy and physical activity of children in the Child and Adolescent Trial for Cardiovascular Health (CATCH). J Health Ed 31(1): 2-9 (2000)
• Nicklas TA, Johnson CC, Myers L. Using a media-marketing campaign for promoting increased awareness about fruit and vegetable consumption among high school students: Gimme 5 Program. J Child Nutr Mgmt 24(1): 27-34 (2000)
• Oginska-Bulik N, Johnson CC. A comparison of anger in cardiovascular high risk and normal adolescents. Acta Universitatis Lodziensis 3: 29-38 (2001)
• Johnson CC, Myers L, Webber LS, Boris NW. Profiles of the adolescent smoker: models of tobacco use among 9th grade high school students: Acadiana Coalition of Teens against Tobacco (ACTT). Prev Med Sep;39(3):551-8 (2004)

Assistant Professor of Medicine
TCC Associate Member
bjovov@tulane.edu
(504) 589-5928, (504) 988-2188 fax
1430 Tulane Ave., SL-35, New Orleans, LA 70112-2699

Biographical Sketch:
Dr. Jovov received her M.D. degree from the University of Sarajevo in Bosnia and Hercegovina. After postdoctoral training at the University of Texas Medical Branch in Galveston, she joined the faculty of the University of Alabama at Birmingham. Dr. Jovov came to Tulane in early 2005. Her major research interest is the role of transmembrane serine proteases and their inhibitors in tumor progression.

Selected Publications:

• Berdiev BK, Jovov B, Ji HL, Tucker W, Naren AP, Fuller CM, Chapman ER, Benos DJ. ENaC subunit-subunit interactions and inhibition by syntaxin 1A. Am J Physiol Renal Physiol, 286:F1100, 2004.
• Jovov B, Tousson A, McMahon LL, Benos DJ. Immunolocalization of acid sensing ion channel 2a in rat cerebellum. Histochem Cell Biol, 119(6):437-46, 2003.
• Berdiev BK, Xia J, McLean LA, Markert JM, Gillespie GY, Mapstone TB, Naren AP, Jovov B, Bubien JK, Ji HL, Fuller CM, Benos DJ. Acid-sensing ion channels in malignant gliomas. J Biol Chem, 287:15023-34, 2003.
• Berdiev BK, Xia J. Jovov B, Markert JM, Mapstone TB, Gillespie GY, Fuller CM, Benos DJ. Protein kinase C isoform antagonism controls BNaC2 (ASICI) function. J Biol Chem, 277:45734-40, 2002.

 

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